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14-3-3ζ Mediates Tau Aggregation in Human Neuroblastoma M17 Cells

Microtubule-associated protein tau is the major component of paired helical filaments (PHFs) associated with the neuropathology of Alzheimer’s disease (AD). Tau in the normal brain binds and stabilizes microtubules. Tau isolated from PHFs is hyperphosphorylated, which prevents it from binding to mic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Tong, Paudel, Hemant K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993442/
https://ncbi.nlm.nih.gov/pubmed/27548710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160635
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