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14-3-3ζ Mediates Tau Aggregation in Human Neuroblastoma M17 Cells
Microtubule-associated protein tau is the major component of paired helical filaments (PHFs) associated with the neuropathology of Alzheimer’s disease (AD). Tau in the normal brain binds and stabilizes microtubules. Tau isolated from PHFs is hyperphosphorylated, which prevents it from binding to mic...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4993442/ https://ncbi.nlm.nih.gov/pubmed/27548710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160635 |
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