Loss of Par3 promotes lung adenocarcinoma metastasis through 14-3-3ζ protein

Partitioning defective protein 3 (Par3) can activate the Tiam1/Rac pathway to inhibit invasion and metastasis in many cancers; however, the role of Par3 in lung adenocarcinoma remains unknown. Here we show that Par3 is downregulated in lung adenocarcinoma tissues and is associated with higher rates...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Tong, Song, Xia, Tian, Fan, Kai, Jiang, Ke, Zhai, Wei, Li, Jing-Song, Wang, Si-Hua, Wang, Jian-Jun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325440/
https://ncbi.nlm.nih.gov/pubmed/27588399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11728
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