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Loss of Par3 promotes lung adenocarcinoma metastasis through 14-3-3ζ protein

Partitioning defective protein 3 (Par3) can activate the Tiam1/Rac pathway to inhibit invasion and metastasis in many cancers; however, the role of Par3 in lung adenocarcinoma remains unknown. Here we show that Par3 is downregulated in lung adenocarcinoma tissues and is associated with higher rates...

Celý popis

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Tong, Song, Xia, Tian, Fan, Kai, Jiang, Ke, Zhai, Wei, Li, Jing-Song, Wang, Si-Hua, Wang, Jian-Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325440/
https://ncbi.nlm.nih.gov/pubmed/27588399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11728
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