Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate

Our understanding on how selective mitochondrial autophagy, or mitophagy, can sustain the archetypal properties of stem cells is incomplete. PTEN-induced putative kinase 1 (PINK1) plays a key role in the maintenance of mitochondrial morphology and function and in the selective degradation of damaged...

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Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Main Authors: Vazquez-Martin, Alejandro, Van den Haute, Chris, Cufí, Sílvia, Corominas-Faja, Bruna, Cuyàs, Elisabet, Lopez-Bonet, Eugeni, Rodriguez-Gallego, Esther, Fernández-Arroyo, Salvador, Joven, Jorge, Baekelandt, Veerle, Menendez, Javier A.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993334/
https://ncbi.nlm.nih.gov/pubmed/27295498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100976
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