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The role of telomeres and telomerase reverse transcriptase isoforms in pluripotency induction and maintenance

Telomeres are linear guanine-rich DNA structures at the ends of chromosomes. The length of telomeric DNA is actively regulated by a number of mechanisms in highly proliferative cells such as germ cells, cancer cells, and pluripotent stem cells. Telomeric DNA is synthesized by way of the ribonucleopr...

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Publicat a:RNA Biol
Autors principals: Teichroeb, Jonathan H., Kim, Joohwan, Betts, Dean H.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993301/
https://ncbi.nlm.nih.gov/pubmed/26786236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1134413
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