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Microenvironmental Regulation of Telomerase Isoforms in Human Embryonic Stem Cells

Recent evidence points to extra-telomeric, noncanonical roles for telomerase in regulating stem cell function. In this study, human embryonic stem cells (hESCs) were cultured in 20% or 2% O(2) microenvironments for up to 5 days and evaluated for telomerase reverse transcriptase (TERT) expression and...

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Detalhes bibliográficos
Main Authors: Radan, Lida, Hughes, Chris S., Teichroeb, Jonathan H., Zamora, Flora M. Vieira, Jewer, Michael, Postovit, Lynne-Marie, Betts, Dean Harvey
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142780/
https://ncbi.nlm.nih.gov/pubmed/24749509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0373
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