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Corticosterone dysregulation exacerbates disease progression in the R6/2 transgenic mouse model of Huntington's disease

Huntington's disease (HD) is a genetic neurological disorder that causes severe and progressive motor, cognitive, psychiatric, and metabolic symptoms. There is a robust, significant elevation in circulating levels of the stress hormone, cortisol, in HD patients; however the causes and consequen...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Dufour, Brett D., McBride, Jodi L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992622/
https://ncbi.nlm.nih.gov/pubmed/27381424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.06.028
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