Palovarotene inhibits heterotopic ossification and maintains limb mobility and growth in mice with the human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) mutation

Fibrodysplasia Ossificans Progressiva (FOP) is a rare and as yet untreatable, genetic disorder of progressive extraskeletal ossification, is the most disabling form of heterotopic ossification (HO) in humans and causes skeletal deformities, movement impairment and premature death. Most FOP patients...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Bone Miner Res
Main Authors: Chakkalakal, Salin A., Uchibe, Kenta, Convente, Michael R., Zhang, Deyu, Economides, Aris N., Kaplan, Frederick S., Pacifici, Maurizio, Iwamoto, Masahiro, Shore, Eileen M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992469/
https://ncbi.nlm.nih.gov/pubmed/26896819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2820
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker