NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in Heart

RATIONALE: Neurofibromin 2 (NF2) is an established tumor suppressor that promotes apoptosis and inhibits growth in a variety of cell types, yet its function in cardiomyocytes remains largely unknown. OBJECTIVE: We sought to determine the role of NF2 in cardiomyocyte apoptosis and ischemia/reperfusio...

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Détails bibliographiques
Publié dans:Circ Res
Auteurs principaux: Matsuda, Takahisa, Zhai, Peiyong, Sciarretta, Sebastiano, Zhang, Yu, Jeong, Jae Im, Ikeda, Shohei, Park, Jiyeon, Hsu, Chiao-Po, Tian, Bin, Pan, Duojia, Sadoshima, Junichi, Del Re, Dominic P.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992450/
https://ncbi.nlm.nih.gov/pubmed/27402866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308586
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