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Regulation of Single Strand Annealing and its role in genome maintenance

Single Strand Annealing (SSA) is a DNA double strand break (DSB) repair pathway that uses homologous repeats to bridge DSB ends. SSA involving repeats that flank a single DSB causes a deletion rearrangement between the repeats, and hence is relatively mutagenic. Nevertheless, this pathway is conserv...

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書目詳細資料
發表在:Trends Genet
Main Authors: Bhargava, Ragini, Onyango, David O., Stark, Jeremy M.
格式: Artigo
語言:Inglês
出版: 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992407/
https://ncbi.nlm.nih.gov/pubmed/27450436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2016.06.007
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