Catalysis of Strand Annealing by Replication Protein A Derives from Its Strand Melting Properties

Eukaryotic DNA-binding protein replication protein A (RPA) has a strand melting property that assists polymerases and helicases in resolving DNA secondary structures. Curiously, previous results suggested that human RPA (hRPA) promotes undesirable recombination by facilitating annealing of flaps pro...

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Hlavní autoři: Bartos, Jeremy D., Willmott, Lyndsay J., Binz, Sara K., Wold, Marc S., Bambara, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490778/
https://ncbi.nlm.nih.gov/pubmed/18522944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800856200
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