The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis

Mitochondrial fatty acid synthesis (FASII) and iron sulfur cluster (FeS) biogenesis are both vital biosynthetic processes within mitochondria. In this study, we demonstrate that the mitochondrial acyl carrier protein (ACP), which has a well-known role in FASII, plays an unexpected and evolutionarily...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Van Vranken, Jonathan G, Jeong, Mi-Young, Wei, Peng, Chen, Yu-Chan, Gygi, Steven P, Winge, Dennis R, Rutter, Jared
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991935/
https://ncbi.nlm.nih.gov/pubmed/27540631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17828
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