Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

Cells harbor two systems for fatty acid synthesis, one in the cytoplasm (catalyzed by fatty acid synthase, FASN) and one in the mitochondria (mtFAS). In contrast to FASN, mtFAS is poorly characterized, especially in higher eukaryotes, with the major product(s), metabolic roles, and cellular function...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Nowinski, Sara M, Solmonson, Ashley, Rusin, Scott F, Maschek, J Alan, Bensard, Claire L, Fogarty, Sarah, Jeong, Mi-Young, Lettlova, Sandra, Berg, Jordan A, Morgan, Jeffrey T, Ouyang, Yeyun, Naylor, Bradley C, Paulo, Joao A, Funai, Katsuhiko, Cox, James E, Gygi, Steven P, Winge, Dennis R, DeBerardinis, Ralph J, Rutter, Jared
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Biochemistry and Chemical Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470841/
https://ncbi.nlm.nih.gov/pubmed/32804083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58041
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