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Role of Nfu1 and Bol3 in iron-sulfur cluster transfer to mitochondrial clients

Iron-sulfur (Fe-S) clusters are essential for many cellular processes, ranging from aerobic respiration, metabolite biosynthesis, ribosome assembly and DNA repair. Mutations in NFU1 and BOLA3 have been linked to genetic diseases with defects in mitochondrial Fe-S centers. Through genetic studies in...

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Melber, Andrew, Na, Un, Vashisht, Ajay, Weiler, Benjamin D, Lill, Roland, Wohlschlegel, James A, Winge, Dennis R
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014551/
https://ncbi.nlm.nih.gov/pubmed/27532773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15991
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