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Inhibition of miR301 enhances Akt-mediated cell proliferation by accumulation of PTEN in nucleus and its effects on cell-cycle regulatory proteins

Micro-RNAs (miRs) represent an innovative class of genes that act as regulators of gene expression. Recently, the aberrant expression of several miRs has been associated with different types of cancers. In this study, we show that miR301 inhibition influences PI3K-Akt pathway activity. Akt overexpre...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Jain, Mayur V., Shareef, Ahmad, Likus, Wirginia, Cieślar-Pobuda, Artur, Ghavami, Saeid, Łos, Marek J.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991504/
https://ncbi.nlm.nih.gov/pubmed/26967567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7996
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