Human-Gyrovirus-Apoptin Triggers Mitochondrial Death Pathway—Nur77 is Required for Apoptosis Triggering

The human gyrovirus derived protein Apoptin (HGV-Apoptin) a homologue of the chicken anemia virus Apoptin (CAV-Apoptin), a protein with high cancer cells selective toxicity, triggers apoptosis selectively in cancer cells. In this paper, we show that HGV-Apoptin acts independently from the death rece...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Chaabane, Wiem, Cieślar-Pobuda, Artur, El-Gazzah, Mohamed, Jain, Mayur V., Rzeszowska-Wolny, Joanna, Rafat, Mehrdad, Stetefeld, Joerg, Ghavami, Saeid, Łos, Marek J.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234882/
https://ncbi.nlm.nih.gov/pubmed/25246270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.08.001
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