Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival

Despite extensive efforts, cancer therapies directed at the Protein Kinase C (PKC) family of serine/threonine kinases have failed in clinical trials. These therapies have been directed at inhibiting PKC and have, in some cases, worsened disease outcome. Here we examine colon cancer patients and show...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dowling, Catríona M., Phelan, James, Callender, Julia A., Cathcart, Mary Clare, Mehigan, Brian, McCormick, Paul, Dalton, Tara, Coffey, John C., Newton, Alexandra C., O'sullivan, Jacintha, Kiely, Patrick A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991501/
https://ncbi.nlm.nih.gov/pubmed/26989024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8062
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