Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors

The resistance to chemotherapy and the tumor escape from host immunosurveillance are the main causes of the failure of anthracycline-based regimens in breast cancer, where an effective chemo-immunosensitizing strategy is lacking. The clinically used aminobisphosphonate zoledronic acid (ZA) reverses...

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Опубликовано в: :Oncotarget
Главные авторы: Kopecka, Joanna, Porto, Stefania, Lusa, Sara, Gazzano, Elena, Salzano, Giuseppina, Pinzòn-Daza, Martha Leonor, Giordano, Antonio, Desiderio, Vincenzo, Ghigo, Dario, De Rosa, Giuseppe, Caraglia, Michele, Riganti, Chiara
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991490/
https://ncbi.nlm.nih.gov/pubmed/26980746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8012
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