Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells

The overexpression of ATP binding cassette (ABC) transporters makes tumor cells simultaneously resistant to several cytotoxic drugs. Impairing the energy metabolism of multidrug resistant (MDR) cells is a promising chemosensitizing strategy, but many metabolic modifiers are too toxic in vivo. We pre...

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Vydáno v:Oncotarget
Hlavní autoři: Kopecka, Joanna, Porto, Stefania, Lusa, Sara, Gazzano, Elena, Salzano, Giuseppina, Giordano, Antonio, Desiderio, Vincenzo, Ghigo, Dario, Caraglia, Michele, De Rosa, Giuseppe, Riganti, Chiara
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741618/
https://ncbi.nlm.nih.gov/pubmed/26372812
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