Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells

The overexpression of ATP binding cassette (ABC) transporters makes tumor cells simultaneously resistant to several cytotoxic drugs. Impairing the energy metabolism of multidrug resistant (MDR) cells is a promising chemosensitizing strategy, but many metabolic modifiers are too toxic in vivo. We pre...

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Foilsithe in:Oncotarget
Main Authors: Kopecka, Joanna, Porto, Stefania, Lusa, Sara, Gazzano, Elena, Salzano, Giuseppina, Giordano, Antonio, Desiderio, Vincenzo, Ghigo, Dario, Caraglia, Michele, De Rosa, Giuseppe, Riganti, Chiara
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2015
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741618/
https://ncbi.nlm.nih.gov/pubmed/26372812
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