Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid

Glioblastomas are highly aggressive adult brain tumors with poor clinical outcome. In the central nervous system (CNS) the blood-brain barrier (BBB) is the most important limiting factor for both development of new drugs and drug delivery. Here, we propose a new strategy to treat glioblastoma based...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Porru, Manuela, Zappavigna, Silvia, Salzano, Giuseppina, Luce, Amalia, Stoppacciaro, Antonella, Balestrieri, Maria Luisa, Artuso, Simona, Lusa, Sara, De Rosa, Giuseppe, Leonetti, Carlo, Caraglia, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279385/
https://ncbi.nlm.nih.gov/pubmed/25431953
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