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Small‐Molecule and Peptide Inhibitors of the Pro‐Survival Protein Mcl‐1

The ability of protein–protein interactions to regulate cellular processes in both beneficial and detrimental ways has made them obvious drug targets. The Bcl‐2 family of proteins undergo a series of protein–protein interactions which regulate the intrinsic cell‐death pathway. The pro‐survival membe...

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Bibliografiske detaljer
Udgivet i:ChemMedChem
Main Authors: Beekman, Andrew M., Howell, Lesley A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991272/
https://ncbi.nlm.nih.gov/pubmed/26696548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500497
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