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Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive, fatal, childhood tumors that arise in the brainstem. DIPGs have no effective treatment, and their location and diffuse nature render them inoperable. Radiation therapy remains the only standard of care for this devastating...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Cancer
Prif Awduron: Amani, Vladimir, Prince, Eric W, Alimova, Irina, Balakrishnan, Ilango, Birks, Diane, Donson, Andrew M., Harris, Peter, Levy, Jean M. Mulcahy, Handler, Michael, Foreman, Nicholas K., Venkataraman, Sujatha, Vibhakar, Rajeev
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991074/
https://ncbi.nlm.nih.gov/pubmed/27538997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2690-6
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