Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma

BACKGROUND: Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive, fatal, childhood tumors that arise in the brainstem. DIPGs have no effective treatment, and their location and diffuse nature render them inoperable. Radiation therapy remains the only standard of care for this devastating...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Amani, Vladimir, Prince, Eric W, Alimova, Irina, Balakrishnan, Ilango, Birks, Diane, Donson, Andrew M., Harris, Peter, Levy, Jean M. Mulcahy, Handler, Michael, Foreman, Nicholas K., Venkataraman, Sujatha, Vibhakar, Rajeev
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991074/
https://ncbi.nlm.nih.gov/pubmed/27538997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2690-6
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