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The inhibition of EZH2 ameliorates osteoarthritis development through the Wnt/β-catenin pathway
The purpose of our study was to elucidate the role of the histone methyltransferase enhancer of zeste homologue 2 (EZH2) in the pathophysiology of osteoarthritis (OA) and to develop a strategy to modulate EZH2 activity for OA treatment. The expression of EZH2 in normal and OA human cartilage was com...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990905/ https://ncbi.nlm.nih.gov/pubmed/27539752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29176 |
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