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Creation of an engineered APC system to explore and optimize the presentation of immunodominant peptides of major allergens
We have generated engineered APC to present immunodominant peptides derived from the major aero-allergens of birch and mugwort pollen, Bet v 1(142–153) and Art v 1(25–36), respectively. Jurkat-based T cell reporter lines expressing the cognate allergen-specific T cell receptors were used to read out...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990899/ https://ncbi.nlm.nih.gov/pubmed/27539532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31580 |
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