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Creation of an engineered APC system to explore and optimize the presentation of immunodominant peptides of major allergens

We have generated engineered APC to present immunodominant peptides derived from the major aero-allergens of birch and mugwort pollen, Bet v 1(142–153) and Art v 1(25–36), respectively. Jurkat-based T cell reporter lines expressing the cognate allergen-specific T cell receptors were used to read out...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Rosskopf, Sandra, Jutz, Sabrina, Neunkirchner, Alina, Candia, Martín R., Jahn-Schmid, Beatrice, Bohle, Barbara, Pickl, Winfried F., Steinberger, Peter
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990899/
https://ncbi.nlm.nih.gov/pubmed/27539532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31580
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