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CloneCNA: detecting subclonal somatic copy number alterations in heterogeneous tumor samples from whole-exome sequencing data
BACKGROUND: Copy number alteration is a main genetic structural variation that plays an important role in tumor initialization and progression. Accurate detection of copy number alterations is necessary for discovering cancer-causing genes. Whole-exome sequencing has become a widely used technology...
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出版年: | BMC Bioinformatics |
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主要な著者: | , , |
フォーマット: | Artigo |
言語: | Inglês |
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BioMed Central
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990858/ https://ncbi.nlm.nih.gov/pubmed/27538789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1174-7 |
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