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CloneCNA: detecting subclonal somatic copy number alterations in heterogeneous tumor samples from whole-exome sequencing data

BACKGROUND: Copy number alteration is a main genetic structural variation that plays an important role in tumor initialization and progression. Accurate detection of copy number alterations is necessary for discovering cancer-causing genes. Whole-exome sequencing has become a widely used technology...

詳細記述

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書誌詳細
出版年:BMC Bioinformatics
主要な著者: Yu, Zhenhua, Li, Ao, Wang, Minghui
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990858/
https://ncbi.nlm.nih.gov/pubmed/27538789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1174-7
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