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CloneCNA: detecting subclonal somatic copy number alterations in heterogeneous tumor samples from whole-exome sequencing data
BACKGROUND: Copy number alteration is a main genetic structural variation that plays an important role in tumor initialization and progression. Accurate detection of copy number alterations is necessary for discovering cancer-causing genes. Whole-exome sequencing has become a widely used technology...
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| Vydáno v: | BMC Bioinformatics |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990858/ https://ncbi.nlm.nih.gov/pubmed/27538789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1174-7 |
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