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Detection of copy number variants and loss of heterozygosity from impure tumor samples using whole exome sequencing data

Using whole-exome sequencing (WES) for the detection of chromosomal aberrations from tumor samples has become increasingly popular, as it is cost-effective and time efficient. However, factors which present in WES tumor samples, including diversity in exon size, batch effect and tumor impurity, can...

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Detaylı Bibliyografya
Yayımlandı:Oncol Lett
Asıl Yazarlar: Liu, Xiaocheng, Li, Ao, Xi, Jianing, Feng, Huanqing, Wang, Minghui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126229/
https://ncbi.nlm.nih.gov/pubmed/30214605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.9150
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