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Deuteration protects asparagine residues against racemization

Racemization in proteins and peptides at sites of L-asparaginyl and L-aspartyl residues contributes to their spontaneous degradation, especially in the biological aging process. Amino acid racemization involves deprotonation of the alpha carbon and replacement of the proton in the opposite stereocon...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Amino Acids
Egile Nagusiak: Lowenson, Jonathan D., Shmanai, Vadim V., Shklyaruck, Denis, Clarke, Steven G., Shchepinov, Mikhail S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990494/
https://ncbi.nlm.nih.gov/pubmed/27169868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-016-2250-z
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