DEUTERATED OXYTOCINS: THE SYNTHESIS AND BIOLOGICAL PROPERTIES OF A CRYSTALLINE ANALOG OF DEAMINO-OXYTOCIN DEUTERATED IN THE 5-ASPARAGINE POSITION

This paper describes the synthesis and biological activity of [5-L-asparagine-α,β,β-d(3)]-deamino-oxytocin. The model peptide S-benzyl-β-mercaptopropionyl-L- asparaginyl-α,β,β-d(3)-glycinamide was also prepared to observe the effect of the conditions of peptide synthesis on the deuterium content. It...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Blomquist, Alfred T., Rich, Daniel H., Carlson, Bruce A., Allen, G. Ashley, Hruby, Victor J., Takashima, Herbert, Nangeroni, Louis L., Glose, Paula, Vigneaud, Vincent Du
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1969
Materias:	Biological Sciences: Biochemistry
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286156/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5263009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.64.1.263
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