DEUTERATED OXYTOCINS: THE SYNTHESIS AND BIOLOGICAL PROPERTIES OF A CRYSTALLINE ANALOG OF DEAMINO-OXYTOCIN DEUTERATED IN THE 5-ASPARAGINE POSITION

This paper describes the synthesis and biological activity of [5-L-asparagine-α,β,β-d(3)]-deamino-oxytocin. The model peptide S-benzyl-β-mercaptopropionyl-L- asparaginyl-α,β,β-d(3)-glycinamide was also prepared to observe the effect of the conditions of peptide synthesis on the deuterium content. It...

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Detalhes bibliográficos
Main Authors: Blomquist, Alfred T., Rich, Daniel H., Carlson, Bruce A., Allen, G. Ashley, Hruby, Victor J., Takashima, Herbert, Nangeroni, Louis L., Glose, Paula, Vigneaud, Vincent Du
Formato: Artigo
Idioma:Inglês
Publicado em: 1969
Assuntos:
Biological Sciences: Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC286156/
https://ncbi.nlm.nih.gov/pubmed/5263009
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