The Non-coding Mammary Carcinoma Susceptibility Locus, Mcs5c, Regulates Pappa Expression via Age-Specific Chromatin Folding and Allele-Dependent DNA Methylation

In understanding the etiology of breast cancer, the contributions of both genetic and environmental risk factors are further complicated by the impact of breast developmental stage. Specifically, the time period ranging from childhood to young adulthood represents a critical developmental window in...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Henning, Amanda N., Haag, Jill D., Smits, Bart M. G., Gould, Michael N.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990333/
https://ncbi.nlm.nih.gov/pubmed/27537370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006261
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