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The Non-coding Mammary Carcinoma Susceptibility Locus, Mcs5c, Regulates Pappa Expression via Age-Specific Chromatin Folding and Allele-Dependent DNA Methylation

In understanding the etiology of breast cancer, the contributions of both genetic and environmental risk factors are further complicated by the impact of breast developmental stage. Specifically, the time period ranging from childhood to young adulthood represents a critical developmental window in...

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Publicado en:PLoS Genet
Main Authors: Henning, Amanda N., Haag, Jill D., Smits, Bart M. G., Gould, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990333/
https://ncbi.nlm.nih.gov/pubmed/27537370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006261
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