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The Non-coding Mammary Carcinoma Susceptibility Locus, Mcs5c, Regulates Pappa Expression via Age-Specific Chromatin Folding and Allele-Dependent DNA Methylation

In understanding the etiology of breast cancer, the contributions of both genetic and environmental risk factors are further complicated by the impact of breast developmental stage. Specifically, the time period ranging from childhood to young adulthood represents a critical developmental window in...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Henning, Amanda N., Haag, Jill D., Smits, Bart M. G., Gould, Michael N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990333/
https://ncbi.nlm.nih.gov/pubmed/27537370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006261
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