The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions

INTRODUCTION: Mechanisms underlying low-penetrance, common, non-protein coding variants in breast cancer risk loci are largely undefined. We showed previously that the non-protein coding mammary carcinoma susceptibility locus Mcs5a/MCS5A modulates breast cancer risk in rats and women. The Mcs5a alle...

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Autori principali: Smits, Bart MG, Sharma, Deepak, Samuelson, David J, Woditschka, Stephan, Mau, Bob, Haag, Jill D, Gould, Michael N
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236344/
https://ncbi.nlm.nih.gov/pubmed/21846333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2933
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