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Mitochondrial Probe Methyltriphenylphosphonium (TPMP) Inhibits the Krebs Cycle Enzyme 2-Oxoglutarate Dehydrogenase

Methyltriphenylphosphonium (TPMP) salts have been widely used to measure the mitochondrial membrane potential and the triphenylphosphonium (TPP(+)) moiety has been attached to many bioactive compounds including antioxidants to target them into mitochondria thanks to their high affinity to accumulate...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Elkalaf, Moustafa, Tůma, Petr, Weiszenstein, Martin, Polák, Jan, Trnka, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990249/
https://ncbi.nlm.nih.gov/pubmed/27537184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161413
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