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Unsolved mystery: the role of BRCA1 in DNA end-joining
Heritable mutations in the tumor suppressor gene BRCA1 increase a woman's lifetime risk of developing breast and ovarian cancer. BRCA1's tumor suppressor function is directly linked to its myriad of functions in the cellular response to DNA double-strand breaks (DSBs). BRCA1 interacts with...
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| Publicado no: | J Radiat Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990114/ https://ncbi.nlm.nih.gov/pubmed/27170701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrw032 |
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