Targeted capture massively parallel sequencing analysis of LCIS and invasive lobular cancer: Repertoire of somatic genetic alterations and clonal relationships

Purpose: Lobular carcinoma in situ (LCIS) has been proposed as a non‐obligate precursor of invasive lobular carcinoma (ILC). Here we sought to define the repertoire of somatic genetic alterations in pure LCIS and in synchronous LCIS and ILC using targeted massively parallel sequencing. Methods: DNA...

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Publicat a:Mol Oncol
Autors principals: Sakr, Rita A., Schizas, Michail, Carniello, Jose V. Scarpa, Ng, Charlotte K.Y., Piscuoglio, Salvatore, Giri, Dilip, Andrade, Victor P., De Brot, Marina, Lim, Raymond S., Towers, Russell, Weigelt, Britta, Reis-Filho, Jorge S., King, Tari A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989916/
https://ncbi.nlm.nih.gov/pubmed/26643573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.11.001
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