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Elevated IL-23R Expression and Foxp3(+)Rorγt(+) Cells in Intestinal Mucosa During Acute and Chronic Colitis

BACKGROUND: IL-23/IL-23R signaling plays a pivotal role during the course of inflammatory bowel diseases (IBD). However, the underlying mechanisms are poorly characterized. Foxp3(+) regulatory T cells are critical in the maintenance of gut immune homeostasis and therefore are important in preventing...

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Pubblicato in:Med Sci Monit
Autori principali: Yang, Jiayin, Xu, Lili
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scientific Literature, Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988365/
https://ncbi.nlm.nih.gov/pubmed/27498708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.896827
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