Involvement of the FoxO1/MuRF1/Atrogin-1 Signaling Pathway in the Oxidative Stress-Induced Atrophy of Cultured Chronic Obstructive Pulmonary Disease Myotubes

Oxidative stress is thought to be one of the most important mechanisms implicated in the muscle wasting of chronic obstructive pulmonary disease (COPD) patients, but its role has never been demonstrated. We therefore assessed the effects of both pro-oxidant and antioxidant treatments on the oxidativ...

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Udgivet i:PLoS One
Main Authors: Pomiès, Pascal, Blaquière, Marine, Maury, Jonathan, Mercier, Jacques, Gouzi, Fares, Hayot, Maurice
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987766/
https://ncbi.nlm.nih.gov/pubmed/27526027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160092
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