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Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming
Erasure of epigenetic memory is required to convert somatic cells towards pluripotency. Reactivation of the inactive X chromosome (Xi) has been used to model epigenetic reprogramming in mouse, but human studies are hampered by Xi epigenetic instability and difficulties in tracking partially reprogra...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987517/ https://ncbi.nlm.nih.gov/pubmed/27507283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12354 |
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