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ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips

Signaling by extracellular signal–regulated kinase (ERK) plays an essential role in the induction of cell motility, but the precise mechanism underlying such regulation has remained elusive. We recently identified SH3P2 as a negative regulator of cell motility whose function is inhibited by p90 ribo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Tanimura, Susumu, Hashizume, Junya, Arichika, Naoya, Watanabe, Kazushi, Ohyama, Kaname, Takeda, Kohsuke, Kohno, Michiaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987290/
https://ncbi.nlm.nih.gov/pubmed/27502487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503123
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