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Pembrolizumab in classical Hodgkin’s lymphoma

Pembrolizumab is a humanized monoclonal antibody directed against programmed cell death protein 1 (PD-1), a key immune-inhibitory molecule expressed on T cells and implicated in CD4+ T-cell exhaustion and tumor immune-escape mechanisms. Classical Hodgkin’s lymphoma (cHL) is a unique B-cell malignanc...

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Bibliografische gegevens
Gepubliceerd in:Eur J Haematol
Hoofdauteurs: Maly, Joseph, Alinari, Lapo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987237/
https://ncbi.nlm.nih.gov/pubmed/27147112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejh.12770
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