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Pembrolizumab and its role in relapsed/refractory classical Hodgkin’s lymphoma: evidence to date and clinical utility

Immune evasion is a critical mechanism of malignant cell survival, and relies in part on molecular signaling through the programmed cell death 1 (PD-1)/PD-1 ligand (PD-L1) axis that contributes to T cell exhaustion. Immune modulatory therapy with monoclonal antibodies against PD-1 designed to enhanc...

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Detalhes bibliográficos
Publicado no:Ther Adv Hematol
Main Authors: Shindiapina, Polina, Alinari, Lapo
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881987/
https://ncbi.nlm.nih.gov/pubmed/29623180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620718761777
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