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Pembrolizumab in classical Hodgkin’s lymphoma
Pembrolizumab is a humanized monoclonal antibody directed against programmed cell death protein 1 (PD-1), a key immune-inhibitory molecule expressed on T cells and implicated in CD4+ T-cell exhaustion and tumor immune-escape mechanisms. Classical Hodgkin’s lymphoma (cHL) is a unique B-cell malignanc...
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Publié dans: | Eur J Haematol |
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Auteurs principaux: | , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987237/ https://ncbi.nlm.nih.gov/pubmed/27147112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejh.12770 |
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