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Therapeutic efficacy of cancer stem cell vaccines in the adjuvant setting

Dendritic cell (DC)-based vaccine strategies aimed at targeting cancer stem-like cells (CSC) may be most efficacious if deployed in the adjuvant setting. In this study, we offer preclinical evidence this is the case for a CSC-DC vaccine as tested in murine models of SCC7 squamous cell cancer and D5...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Hu, Yangyang, Lu, Lin, Xia, Yang, Chen, Xin, Chang, Alfred E., Hollingsworth, Robert E, Hurt, Elaine, Owen, John, Moyer, Jeffrey S., Prince, Mark E.P., Dai, Fu, Bao, Yangyi, Wang, Yi, Whitfield, Joel, Xia, Jian-chuan, Huang, Shiang, Wicha, Max S., Li, Qiao
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987233/
https://ncbi.nlm.nih.gov/pubmed/27325649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2664
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