Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells

We identified cancer stem cell (CSC)-enriched populations from murine melanoma D5 syngeneic to C57BL/6 mice and the squamous cancer SCC7 syngeneic to C3H mice using ALDEFLUOR/ALDH as a marker, and tested their immunogenicity using the cell lysate as a source of antigens to pulse dendritic cells (DCs...

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Autors principals: Li, Qiao, Lu, Lin, Tao, Huimin, Xue, Carolyn, Teitz-Tennenbaum, Seagal, Owen, John H., Moyer, Jeffrey S, Prince, Mark E.P., Chang, Alfred E., Wicha, Max S.
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2014
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063547/
https://ncbi.nlm.nih.gov/pubmed/24430104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50561
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