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PTRF/Cavin-1 promotes efficient ribosomal RNA transcription in response to metabolic challenges

Ribosomal RNA transcription mediated by RNA polymerase I represents the rate-limiting step in ribosome biogenesis. In eukaryotic cells, nutrients and growth factors regulate ribosomal RNA transcription through various key factors coupled to cell growth. We show here in mature adipocytes, ribosomal t...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Liu, Libin, Pilch, Paul F
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987143/
https://ncbi.nlm.nih.gov/pubmed/27528195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17508
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