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Cavin-1/PTRF mediates insulin-dependent focal adhesion remodeling and ameliorates high-fat diet–induced inflammatory responses in mice
Cavin-1/polymerase I and transcript release factor (PTRF) is a requisite component of caveolae, small plasma membrane invaginations that are highly abundant in adipocytes. Cavin-1 is a dynamic molecule whose dissociation from caveolae plays an important role in mechanoprotection and rRNA synthesis....
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615684/ https://ncbi.nlm.nih.gov/pubmed/31126986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008824 |
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