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Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
Proteasomes are essential for protein homeostasis in eukaryotes. To preserve cellular function, transcription of proteasome subunit genes is induced in response to proteasome dysfunction caused by pathogen attacks or proteasome inhibitor drugs. In Caenorhabditis elegans, this response requires SKN-1...
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| Publicado no: | eLife |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987142/ https://ncbi.nlm.nih.gov/pubmed/27528192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17721 |
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