Enhanced Pulmonary Vascular and Alveolar Development via Prenatal Administration of a Slow-Release Synthetic Prostacyclin Agonist in Rat Fetal Lung Hypoplasia

Lung hypoplasia and pulmonary hypertension are the major causes of mortality in neonates with congenital diaphragmatic hernia (CDH). Although the prostaglandin pathway plays a pivotal role in lung development, the reported efficacy of postnatal prostaglandin agonist treatment is suboptimal. We hypot...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Umeda, Satoshi, Miyagawa, Shigeru, Fukushima, Satsuki, Oda, Noriko, Saito, Atsuhiro, Sakai, Yoshiki, Sawa, Yoshiki, Okuyama, Hiroomi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987057/
https://ncbi.nlm.nih.gov/pubmed/27529478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161334
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